Changes in magnetic resonance (MR) signals during interstitial microwave heating are reported, and correlated with simultaneously acquired temperature readings from three fiber-optic probes implanted in a polyacrylamide gel phantom. The heating by a MR-compatible microwave antenna did not interfere with simultaneous MR image data acquisition. MR phase-difference images were obtained using a fast two-dimensional-gradient echo sequence. From these images the temperature-sensitive resonant frequency of the 1H nuclei was found to decrease approximately by 0.008 ppm/°C. The method and results presented here demonstrate that noninvasive MR-temperature imaging can be performed simultaneously with interstitial microwave thermal treatment
Vitkin, I.A.; Moriarty, J.A.; Peters, R.D.; Kolios, Michael C.; Gladman, A.S.; Chen, J.C.; Hinks, R.S.; Hunt, J.W.; Wilson, B.C.; Easty, A.C.; Bronskill, M.J.; Kucharczyk, W.; Sherar, M.D.; and Henkelman, R.M., "Magnetic Resonance Imaging of Temperature Changes During Interstitial Microwave Heating: A Phantom Study" (1997). Physics Publications and Research. Paper 1.