The high frequency backscatter from cells with a nucleus to cell volume ratio of 0.50 cannot be adequately modeled as a homogeneous sphere. It was hypothesized that the cytoplasm of such cells is of fluid nature. This work attempts to model the ultrasound backscatter 10–62 MHz from some non-nucleated biological specimens. This was done by measuring the backscatter response from individual sea urchin oocytes and comparing it to theoretical predictions in both the time and frequency domains. A good agreement was found between the experimental and theoretical results suggesting that the non-nucleated oocytes are of fluid nature.
Falou, Omar; Baddour, Ralph E.; Nathanael, George; Czarnota, Gregory J.; Kumaradas, J Carl; and Kolios, Michael C., "A Study of High Frequency Ultrasound Scattering from Non-nucleated Biological Specimens" (2008). Physics Publications and Research. Paper 5.